Melanoma is one of the most common skin cancers and affects the cells that
produce human skin pigment. Usually caused through long exposure to sunlight,
melanoma can turn into serious cancer if it is allowed to spread.
Risks & Symptoms
Melanin is the skin pigment that creates color in the skin and protects
the skin from UV rays and other environmental factors. Melanoma occurs
when melanocytes, the cells that produce melanin become cancerous and
begin dividing uncontrollably. Usually, melanoma is characterized by a
mole that grows suddenly, changes color or begins to itch or bleed. Sudden
changes in skin color or the texture of the skin can also point to the
development of cancer. If this occurs, speak to your doctor.
Although it is unclear what exactly causes melanoma, individuals who are
exposed unprotected to sunlight and UV rays for long periods are at a
much greater risk of developing melanoma. Those who have weakened immune
systems or who have a greater amount of moles are at greater risk. Lighter-skinned
individuals are also more susceptible to the development of melanoma than
darker-skinned individuals because the presence of greater amounts of
melatonin in the skin seems to have a protective effect. Individuals with
fairer skin should wear sunscreen and get regular screenings. This is
especially important as patients age.
Diagnosis & Staging
To diagnose melanoma, a biopsy will be required. Usually, melanoma will
be a brown or black color where the cancer is developing and most often
occurs on the skin. However, the back of the eye or the nails and soles
of the feet have also been known to develop melanoma. Melanoma may look
just like a spot or develop into a lesion.
To determine whether the lesion is cancerous, it is removed and then tested.
The dangerousness of melanoma is dependent on how deep cancer has invaded
the skin. Your doctor will determine this using two systems developed
by Breslow and Clark. Breslow looked at how far cancer had invaded the
skin by millimeters and Clarke tried to determine which levels of the
skin had been infected. Based on these results your doctor will develop
a proper treatment plan.
A biopsy is usually enough to determine the presence of melanoma. However,
if cancer has spread deeply into the skin, your doctor may recommend an
X-ray or PET scan to determine the extent of the metastasis. When melanoma
spreads beyond the skin, it usually spreads through the lymph node system.
So, your doctor may recommend a sentinel lymph node biopsy.
Treatment Options
Treatments for melanoma include surgery, chemotherapy, radiation therapy
and immunotherapy. However, surgery is the most common option. Usually,
the melanoma is removed through an incision that is less than a millimeter
thick. If the cancer has spread, immunotherapy, chemotherapy or radiation
therapy may be used to treat it. Chemotherapy use has increased in recent
years as doctors have been able to target chemotherapy only towards those
cells that have melanoma DNA mutations present in their gene pool. Immunotherapy
is also being used more frequently to treat melanoma. If your doctor determines
that you are a good candidate, one of two drugs will be administered to
you to see if your immune system can be triggered to fight melanoma.
Call (251) 435-2273 today to speak with one of our experts about your
treatment options.